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Fisher Core and Linker Histone Modifications Involved in the DNA Damage Response .
Chubb and Stephen Rea Chromatin Assembly and Signalling the End of DNA Repair Requires Acetylation of Histone H3 on Lysine 56 .
165 Emmanuele Crespan, Alessandra Amoroso, and Giovanni Maga DNA Polymerase η, a Key Protein in Translesion Synthesis in Human Cells .
Teresa Wang the Klaus-Bensch Professor of Pathology Stanford University, California, to celebrate her life-long achievements in the fields of Genome Stability and Cell Cycle Regulation Preface Since the discovery of the DNA structure by Crick, Franklin, Watson and Wilkins in 1953 and even before researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders (Franklin and Gosling, 1953; Watson and Crick, 1953a, b; Wilkins et al., 1953a, b).
In addition, these publica- tions were the foundation of a new research stream coined “Molecular Biology”. Pelc published a nearly as fundamental discovery when they discovered DNA replication as a timely scheduled process between two cell divisions and coined the names G1, S and G2 phase introducing the concept of the eukaryotic cell cycle (Howard and Pelc, 1953). (1953a) Genetical implications of the structure of deoxyribonucleic acid.
She contributed numerous milestones to the field such as cloning and expressing the first human replicative DNA polymerase, study regulation of replication proteins in the cell cycle, in dependence of proliferation and after DNA damage to name a few.
During her research career, she has served as a role model for a huge number of life scientists, who work in her group but also interacted with her at all stages of their research career. Teresa Wang to whom this book is dedicated was not only an exceptional scientist but was honored with numerous awards including the Klaus-Bensch Professorship of Pathology at Stanford University.
Despite her busy university life she also found time to look after her family including her mother, her husband and raising two chil- dren. (1953) Evidence for 2-chain helix in crystalline structure of sodium deoxyribonucleate.
During my research career at for me an especially sensitive decision-making time I was one of these lucky ones, who spent time in her lab and published some of vii viii Preface my most important discoveries with her.
And I can only write in short: “Thank you very much, Teresa, for all your support and help throughout my scientific career.” Galway, Ireland Heinz Peter Nasheuer July 2009 References Franklin, R.
(1953b) Molecular structure of deoxypentose nucleic acids. Contents Coming Full Circle: Cyclin-Dependent Kinases as Anti-cancer Drug Targets .
During her career Teresa Wang was one of the scientists, who with great success has enhanced our understanding of cancer cell biology since the early1970s when the American President Richard Nixon proclaimed the “War on Cancer”.
It was nearly at the same time when Teresa Wang started her career at Stanford University where her main research focus has been in the fields of cell growth, cell division and genome stability. (1953) Synthesis of deoxyribonucleic acid in normal and irradiated cells and its relation to chromosome breakage.
Sullivan Nucleotide Excision Repair in Higher Eukaryotes: Mechanism of Primary Damage Recognition in Global Genome Repair .Tags: Adult Dating, affair dating, sex dating